Fig. 25.14a 75Se Selenocholesterol adrenocortical imaging in Conn's syndrome. The image is a posterior view of the abdomen in a patient with Conn's syndrome (primary aldosteronism). It reveals high uptake of 75Se selenocholesterol in the right adrenal cortex, shown in red and yellow, as compared to the normal uptake in the left adrenal cortex, shown in blue. Production of aldosterone by a Conn's adenoma does not suppress the uptake of 75Se selenocholesterol by the normal adrenal. The purpose of adrenal cortical imaging is to localise an adenoma or demonstrate bilateral hyperplasia once a positive diagnosis has been made of Conn's or Cushing's syndrome, clinically and biochemically.